Methodological and Statistical Problems in Sleep Apnea Research: The Literature on Uvulopalatopharyngoplasty

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Effect of uvulopalatopharyngoplasty on positional dependency in obstructive sleep apnea.

OBJECTIVE To assess the effect of uvulopalatopharyngoplasty (UPPP) on positional dependency in patients with obstructive sleep apnea (OSA). DESIGN Retrospective analysis. SETTING Tertiary care university hospital. PATIENTS Ninety-six patients who underwent UPPP because of OSA from June 1, 2004, through July 31, 2008, were included. Both preoperative and postoperative attended full-night p...

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Effect of Isolated Uvulopalatopharyngoplasty on Subjective Obstructive Sleep Apnea Symptoms

OBJECTIVES The aims of this study were 1) to evaluate the effect of isolated uvulopalatopharyngoplasty (UPPP) on subjective obstructive sleep apnea (OSA) symptoms in adult patients regardless of the response to surgery, and ultimately 2) to investigate the differences in changes in subjective OSA symptoms between successful and unsuccessful surgery groups. METHODS Twenty consecutive adult pat...

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The acute effects of uvulopalatopharyngoplasty on breathing during sleep in sleep apnea patients.

Uvulopalatopharyngoplasty (UPPP) is frequently employed in the treatment of obstructive sleep apnea (OSA). Despite anecdotal reports of early post-UPPP deaths and the recommendation by some authors to perform a prophylactic tracheotomy for selected patients at the time of UPPP, there has been no systematic examination of breathing during sleep in the early post-UPPP period. In order to evaluate...

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Outcomes for multilevel surgery for sleep apnea: Obstructive sleep apnea, transoral robotic surgery, and uvulopalatopharyngoplasty.

OBJECTIVES/HYPOTHESIS This study evaluates the outcomes of multilevel surgery for patients with obstructive sleep apnea (OSA) who underwent transoral robotic surgery (TORS) (i.e., posterior glossectomy and limited lateral pharyngectomy) with uvulopalatopharyngoplasty (UPPP). STUDY DESIGN Prospective, nonrandomized trial with historical controls. METHODS All patients underwent pre- and posto...

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Mechanisms Underlying Improvement in Obstructive Sleep Apnea Syndrome by Uvulopalatopharyngoplasty

In a previous case report, we determined for the first time that uvulopalatopharyngoplasty (UPPP) does not change the volume of the upper airway but causes morphological changes in the entire upper airway. The objective of this study is to elucidate the mechanisms underlying the improvement in obstructive sleep apnea syndrome (OSAS) by UPPP. We present an additional case involving a patient wit...

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ژورنال

عنوان ژورنال: Sleep

سال: 1995

ISSN: 1550-9109,0161-8105

DOI: 10.1093/sleep/18.8.659